DNA methylation in maternal, fetal and neonatal rat tissues following perinatal administration of procarbazine
✍ Scribed by O. D. Wiestler; P. Kleihues; J. M. Rice; S. Ivankovic
- Book ID
- 112293873
- Publisher
- Springer-Verlag
- Year
- 1984
- Tongue
- English
- Weight
- 398 KB
- Volume
- 108
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Formation and loss of methylated purines in DNA of various fetal and maternal tissues were measured up to 7 days following intravenous administration of __N__‐[^14^C]methyl‐__N__‐nitrosourea to rats on the 21st day of gestation. Methylation products were detected in all tissues examined
Cadmium (Cd) and zinc (Zn) concentrations were determined by solid sampling atomic absorption spectrometry (AAS) in rat maternal and fetal tissues after exposure to cadmium. Cadmium was administered subcutaneously as CdCl2 in saline daily during pregnancy. Two experiments were performed. In expt. I
## Abstract Pregnant BD‐IX rats (21st day of gestation) received a single IV injection (15 mg/kg) of tritiated 7,12‐dimethylbenz(__a__)anthracene (DMBA), a dose known to induce a high incidence of nervous‐system tumors in the offspring. The animals were killed 12 h later and hydrocarbon‐deoxyribonu