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Dimethyl Sulfate Uptake and Methylation of DNA in Rat Respiratory Tissues Following Acute Inhalation

✍ Scribed by Brian H. Mathison; Marie L. Taylor; Matthew S. Bogdanffy

Book ID: 115608547
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 586 KB
Volume: 28
Category: Article
ISSN: 0272-0590
DOI: 10.1006/faat.1995.1166

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## Abstract Formation and loss of methylated purines in DNA of various fetal and maternal tissues were measured up to 7 days following intravenous administration of __N__‐[^14^C]methyl‐__N__‐nitrosourea to rats on the 21st day of gestation. Methylation products were detected in all tissues examined