Uptake, Tissue Distribution, and Excretion of 14 C-Sulfur Mustard Vapor Following Inhalation in F344 Rats and Cutaneous Exposure in Hairless Guinea Pigs

Reduction of erythema in hairless guinea

Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin

✍ Jeffrey J. Yourick; Jeffrey S. Dawson; Larry W. Mitcheltree 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 564 KB

Erythema is the initial symptom that occurs after sulfur mustard (HD) cutaneous exposure. The time course of HD-induced erythema is similar to that observed after W irradiation, which can be reduced by indomethacin. Sulfur mustard lethality is decreased by using promethazine, which is an antihistami