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DNA-like double helix formed by peptide nucleic acid

✍ Scribed by Wittung, Pernilla; Nielsen, Peter E.; Buchardt, Ole; Egholm, Michael; Norde´n, Bengt

Book ID
109788214
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
406 KB
Volume
368
Category
Article
ISSN
0028-0836

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Peptide Nucleic Acids (PNAs) are DNA mimics in which the chiral monomer inserted in the middle of the strand is able to induce a strong preference in the helix handedness of a deoxyribose phosphate backbone has been replaced by a pseudo-peptide skeleton composed of N-(2-aminoethyl)-PNA-PNA duplex. T