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A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex

✍ Scribed by Betts, L.; Josey, J. A.; Veal, J. M.; Jordan, S. R.


Book ID
121155539
Publisher
American Association for the Advancement of Science
Year
1995
Tongue
English
Weight
545 KB
Volume
270
Category
Article
ISSN
0036-8075

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Peptide Nucleic Acids (PNAs) are DNA mimics in which the chiral monomer inserted in the middle of the strand is able to induce a strong preference in the helix handedness of a deoxyribose phosphate backbone has been replaced by a pseudo-peptide skeleton composed of N-(2-aminoethyl)-PNA-PNA duplex. T