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Peptide Nucleic Acid (PNA): A Pseudopeptide with DNA-like Properties

✍ Scribed by Peter E. Nielsen; Uffe Koppelhus; Frederik Beck

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of a Monocharged Peptide Nucleic Acid (PNA) Analogue and Its Recognition as Substrate by DNA Polymerases. -The preparation of a novel phosphoramidite monomer based on thyminyl acetic acid coupled to a secondary nitrogen of 2-(2-amino-ethylamino)ethanol (III) is described. This monomer can