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DNA damage and repair in gastric cancer—A correlation with the hOGG1 and RAD51 genes polymorphisms

✍ Scribed by Tomasz Poplawski; Michal Arabski; Dorota Kozirowska; Maria Blasinska-Morawiec; Zbigniew Morawiec; Alina Morawiec-Bajda; Grażyna Klupińska; Arkadiusz Jeziorski; Jan Chojnacki; Janusz Blasiak

Book ID
113808894
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
225 KB
Volume
601
Category
Article
ISSN
0027-5107

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## Abstract Oxidative DNA damage is thought to play an important part in the pathogenesis of __H. pylori__‐induced mucosal damage. 8‐OHdG is a sensitive marker of DNA oxidation and is repaired by a polymorphic glycosylase (__OGG1__) more effectively than by __OGG1__‐Cys^326^. The aims of this study