✦ LIBER ✦

DNA Adduct Levels and Intestinal Lesions in Congenic Rapid and Slow Acetylator Syrian Hamsters Administered the Food Mutagens 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ

✍ Scribed by Steffensen, Inger-Lise ;Fretland, Adrian J. ;Paulsen, Jan Erik ;Feng, Yi ;Eide, Tor Jacob ;Devanaboyina, Udaya-Sankar ;Hein, David W. ;Alexander, Jan

Book ID: 110754822
Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 85 KB
Volume: 86
Category: Article
ISSN: 0901-9928
DOI: 10.1111/j.0901-9928.2000.860603.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

DNA adduct levels and absence of tumors

DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

✍ Adrian J. Fretland; Uday S. Devanaboyina; Norma A. Nangju; Matthew A. Leff; Gong 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 2 views

Specificity of base substitution mutatio

Specificity of base substitution mutations induced by the dietary carcinogens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in Salmonella

✍ W.H. Koch; R.W. Wu; T.A. Cebula; J.S. Felton 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

The base pair substitution mutational profiles in-position (CCCrCTC; 96-99% of total). Base substiduced by the heterocyclic amine cooked food muta-tution mutagenesis induced by heterocyclic amines gens PhIP and IQ in Salmonella typhimurium strains related to PhIP is generally SOS-dependent, requir-T

Inhibition of plasmid reporter gene expr

Inhibition of plasmid reporter gene expression in cho cells by DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5–b]pyridine

✍ Liju Fan; Elizabeth G. Snyderwine 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 667 KB

## Abstract 2‐Amino‐3‐methylimidazo[4,5‐f]quinoline (IQ) and 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__)]pyridine (PhIP) are two members of a family of carcinogenic heterocyclic amines (HAs) found in cooked meats that form DNA adducts after activation to __N__‐acetoxy derivatives. The ability of IQ

One dose of 2-amino-1-methyl-6-phenylimi

One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene

✍ Åshild Andreassen; Linda Møllersen; Rose Vikse; Inger-Lise Steffensen; Arne Mika 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 89 KB

DNA adducts formed by the food mutagen 2

DNA adducts formed by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in vitro and in vivo. Identification of a PhIP-2-deoxyguanosine adduct

✍ H. Frandsen; S. Grivas; L. Dragsted; J.C. Larsen 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 87 KB

Inhibition of DNA adduct formation of 2-

Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3-methylimidazo[4,5-f]quinoline by dietary indole-3-carbinol in female rats

✍ Ying-Hui He; Herman A.J. Schut 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 171 KB 👁 1 views

2-Amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP) and 2-amino-3-methylimidazo[4,5f]quinoline (IQ) are two important heterocyclic amines formed in proteinaceous foods during the cooking process. Both PhIP and IQ are carcinogenic in several strains of rats. PhIP induces mammary tumors in female F3