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DNA adduct formation from the mutagenic air pollutant 3-nitrobenzanthrone

✍ Scribed by Christian A Bieler; Manfred Wiessler; Lothar Erdinger; Hitomi Suzuki; Takeji Enya; Heinz H Schmeiser

Book ID
117767753
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
108 KB
Volume
439
Category
Article
ISSN
1383-5718

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## Abstract 3‐nitrobenzanthrone (3‐NBA) is an extremely potent mutagen in the Salmonella reversion assay and a suspected human carcinogen identified in diesel exhaust and in ambient airborne particulate matter. To evaluate the in vivo mutagenicity of 3‐NBA, we analyzed the mutant frequency (MF) in

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## Abstract 3‐Nitrobenzanthrone (3‐NBA) is an environmental pollutant and suspected human carcinogen found in emissions from diesel and gasoline engines and on the surface of ambient air particulate matter; human exposure to 3‐NBA is likely to occur primarily via the respiratory tract. In our study