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Diversity-Oriented Synthesis of Enantiopure N-Protected β,β-Dialkylserines.

✍ Scribed by James E. Dettwiler; William D. Lubell


Book ID
101965341
Publisher
John Wiley and Sons
Year
2004
Weight
208 KB
Volume
35
Category
Article
ISSN
0931-7597

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A facile synthesis of chiral N-protected
✍ Marc Rodriguez; Muriel Llinares; Sylvie Doulut; Annie Heitz; Jean Martinez 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 211 KB

Chiral N-protected p-amino alcohols are easily obtained by NaB& reduction of mixed anhydndes of N-protected a-ammo acids m an organic/aqueous medium. The alcohols obtamed from side chain or main chain reduction of N-protected asparhc acid are converted in good yields into lactones.