Diureas as Ligands in Asymmetric Reduction of Ketones
β Scribed by Gamez, Patrick; Dunjic, Branko; Lemaire, Marc
- Book ID
- 121225592
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 181 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The catalytic enantioselective reduction of prochiral ketones using a chiral thiourea as ligand is reported. Several metallic precursors were tested. e.e.'s up to 94% are obtained with a ruthenium complex.
1997 stereochemistry stereochemistry (general, optical resolution) O 0030 30 -032 Chiral Thiourea as Ligand for the Asymmetric Reduction of Prochiral Ketones. -Prochiral ketones are reduced enantioselectively using the chiral thiourea ligand CTU with various metal catalysts. Best yields and selectiv
Bimorpholine and 3,3%-bimorpholine were used as chiral ligands in Rh-mediated asymmetric hydride transfer reduction of prochiral aromatic ketones affording corresponding alcohols with good ee (up to 75%).