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Chiral thiourea as ligand for the asymmetric reduction of prochiral ketones

✍ Scribed by François Touchard; Patrick Gamez; Fabienne Fache; Marc Lemaire


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
265 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


The catalytic enantioselective reduction of prochiral ketones using a chiral thiourea as ligand is reported. Several metallic precursors were tested. e.e.'s up to 94% are obtained with a ruthenium complex.


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