1997 stereochemistry stereochemistry (general, optical resolution) O 0030 30 -032 Chiral Thiourea as Ligand for the Asymmetric Reduction of Prochiral Ketones. -Prochiral ketones are reduced enantioselectively using the chiral thiourea ligand CTU with various metal catalysts. Best yields and selectiv
✦ LIBER ✦
Chiral thiourea as ligand for the asymmetric reduction of prochiral ketones
✍ Scribed by François Touchard; Patrick Gamez; Fabienne Fache; Marc Lemaire
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 265 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The catalytic enantioselective reduction of prochiral ketones using a chiral thiourea as ligand is reported. Several metallic precursors were tested. e.e.'s up to 94% are obtained with a ruthenium complex.
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