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Distribution of Plasma Carbamazepine in Epileptic Patients

โœ Scribed by Shosuke Watanabe; Chie Kuyama; Shigeo Yokoyama; Shinsuke Kubo; Hiroyuki Iwai

Book ID
118707440
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
487 KB
Volume
31
Category
Article
ISSN
1323-1316

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Distribution of carbamazepine and its ep
Distribution of carbamazepine and its epoxide in blood compartments in adolescent and adult epileptic patients
โœ J. Bonneton; P. Genton; Dr E. Mesdjian ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 331 KB

Carbamazepine (CBZ) used in the treatment of epilepsy, is metabolized in man to an active metabolite: carbamazepine 10-1 1 epoxide (CBZ-E). CBZ and CBZ-E concentrations in the different blood compartments (plasma ultrafiltrate, plasma proteins, and red blood cells (RBC)) of epileptic patients on CBZ