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Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients

✍ Scribed by M. L. Friis; J. Christiansen; E. F. Hvidberg

Publisher: Springer
Year: 1978
Tongue: English
Weight: 367 KB
Volume: 14
Category: Article
ISSN: 0031-6970
DOI: 10.1007/bf00560257

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Carbamazepine-lO,l l-epoxide is a metabolite of carbamazepine that has been identified in the urine OT the rat and in the urine and plasma of marV and which, in the rat, has been shown to have antiepileptic properties comparable to those of the parent drug. It has therefore been suggested3 that, in