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Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer

✍ Scribed by Marchoudi, N.; Amrani Hassani Joutei, H.; Jouali, F.; Fekkak, J.; Rhaissi, H.


Book ID
121278394
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
294 KB
Volume
61
Category
Article
ISSN
0369-8114

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## Abstract Mutational analysis of __KRAS__ codons 12 and 13 is standard for patients with metastatic colorectal cancer since mutations in these codons predict lack of response to anti‐EGFR therapies. However, even among patients whose tumors are wildtype for __KRAS__ codons 12 and 13, only a subse