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DISTRIBUTION AND METABOLISM OF (5-HYDROXYMETHYL)FURFURAL IN MALE F344 RATS AND B6C3F1 MICE AFTER ORAL ADMINISTRATION

โœ Scribed by Veronica B. Godfrey, Ling-Jen Chen,,

Book ID
126606991
Publisher
Taylor and Francis Group
Year
1999
Tongue
English
Weight
165 KB
Volume
57
Category
Article
ISSN
1087-2620

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โœ Richard D. Irwin; Scot L. Eustis; Steven Stefanski; Joseph K. Haseman ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 740 KB

Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr