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Distinctive differences in DNA double-strand break repair between normal urothelial and urothelial carcinoma cells

✍ Scribed by Frank Windhofer; Sabine Krause; Christiane Hader; Wolfgang A. Schulz; Andrea R. Florl


Book ID
113809111
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
660 KB
Volume
638
Category
Article
ISSN
0027-5107

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The end-joining pathway of DNA double-strand break (DSB) repair is necessary for proper V(D)J recombination and repair of DSB caused by ionizing radiation. This DNA repair pathway can either use short stretches of (micro)homology near the DNA ends or use no homology at all (direct end-joining). We d