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The Difference of DNA Double-strand Break Repair between Neurons and Microglia in Brain Tissue

✍ Scribed by Dong, X.; Ruebe, C.; Martin, K.; Dong, J.; Wu, G.


Book ID
108148524
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
57 KB
Volume
72
Category
Article
ISSN
0360-3016

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The end-joining pathway of DNA double-strand break (DSB) repair is necessary for proper V(D)J recombination and repair of DSB caused by ionizing radiation. This DNA repair pathway can either use short stretches of (micro)homology near the DNA ends or use no homology at all (direct end-joining). We d