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Homologous Recombination between Heterologs during Repair of a Double-Strand Break: Suppression of Translocations in Normal Cells

✍ Scribed by CHRISTINE RICHARDSON; MARY ELLEN MOYNAHAN; MARIA JASIN

Book ID: 111395730
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 582 KB
Volume: 886
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1999.tb09412.x

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## Abstract Abnormal activation of cellular DNA repair pathways by deregulated signaling of receptor tyrosine kinase systems has broad implications for both cancer biology and treatment. Recent studies suggest a potential link between DNA repair and aberrant activation of the hepatocyte growth fact