We studied the repair of double-strand breaks (DSB) in plasmid DNA introduced into haploid cells of the yeast Saccharomyces cerevisiae. The efficiency of repair was estimated from the frequency of transformation of the cells by an autonomously replicated linearized plasmid. The frequency of "lithium
Influence of non-homology between recombining DNA sequences on double-strand break repair in Saccharomyces cerevisiae
β Scribed by Glasunov, Alexander ;Frankenberg-Schwager, Marlis ;Frankenberg, Dieter
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 644 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0026-8925
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Abnormal activation of cellular DNA repair pathways by deregulated signaling of receptor tyrosine kinase systems has broad implications for both cancer biology and treatment. Recent studies suggest a potential link between DNA repair and aberrant activation of the hepatocyte growth fact
## Summary Doubleβstrand breaks (DSB) strongly enhance homologous recombination in the genome of somatic plant cells. To characterize the mechanism of homologous DSB repair in detail, __Agrobacterium__βmediated targeting experiments were performed in tobacco, with repair constructs being homologous
The formation and repair of double-strand breaks induced in DNA by MMS was studied in haploid wild type and MMS-sensitive rad6 mutant strains of Saccharomyces cerevisiae with the use of the neutral and alkaline sucrose sedimentation technique. A similar decrease in average molecular weight of double