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Distinct gene expression profiling in chronic lymphocytic leukemia with 11q23 deletion

✍ Scribed by Aalto, Y; El-Rifai, W; Vilpo, L; Ollila, J; Nagy, B; Vihinen, M; Vilpo, J; Knuutila, S

Book ID: 110055038
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 449 KB
Volume: 15
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2402282

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## Abstract Deletion of chromosome region 11q22–q23 defines a subgroup of patients with B‐cell chronic lymphocytic leukemia (B‐CLL) characterized by poor survival. Although the tumor‐suppressor gene __ATM__ in the consensus deletion region was found to be biallelically inactivated in about one thir