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Discontinuous deletions at 11q23 in B cell chronic lymphocytic leukemia

✍ Scribed by Zhu, Y; Monni, O; El-Rifai, W; Siitonen, SM; Vilpo, L; Vilpo, J; Knuutila, S


Book ID
110054198
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
93 KB
Volume
13
Category
Article
ISSN
0887-6924

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## Abstract Deletion of chromosome region 11q22–q23 defines a subgroup of patients with B‐cell chronic lymphocytic leukemia (B‐CLL) characterized by poor survival. Although the tumor‐suppressor gene __ATM__ in the consensus deletion region was found to be biallelically inactivated in about one thir