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A 23-year-old woman with 11q-chronic lymphocytic leukemia

✍ Scribed by Carlos Eduardo Miguel; Fábio Morato de Oliveira; Sabrina Dias Leite-Cueva; Eduardo Magalhães Rego; Roberto Passetto Falcão


Book ID
107577167
Publisher
Springer US
Year
2010
Tongue
English
Weight
217 KB
Volume
28
Category
Article
ISSN
1357-0560

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## Abstract Deletion of chromosome region 11q22–q23 defines a subgroup of patients with B‐cell chronic lymphocytic leukemia (B‐CLL) characterized by poor survival. Although the tumor‐suppressor gene __ATM__ in the consensus deletion region was found to be biallelically inactivated in about one thir