𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

✍ Scribed by Hessling, Martin; Richter, Klaus; Buchner, Johannes

Book ID
109965648
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
715 KB
Volume
16
Category
Article
ISSN
1545-9993

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

HSP90 and the chaperoning of cancer
HSP90 and the chaperoning of cancer
✍ Whitesell, Luke; Lindquist, Susan L. πŸ“‚ Article πŸ“… 2005 πŸ› Nature Publishing Group 🌐 English βš– 444 KB
Geldanamycin, an inhibitor of the chaper
Geldanamycin, an inhibitor of the chaperone activity of HSP90, induces MAPK-independent cell cycle arrest
✍ Monique Bedin; Anne-Marie Gaben; CΓ©cile Saucier; Jan Mester πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 292 KB

The effects of GA, an ansamycin antibiotic in development as a lead anticancer drug, were studied in mouse BP-A31 fibroblasts and in human cancer-derived cell lines. GA and related molecules act by inhibiting the chaperone function of the Hsp90 protein through competition for ATP binding. The antipr