Disease genetics: Tools to exploit familial data
β Scribed by Stower, Hannah
- Book ID
- 127249180
- Publisher
- Nature Publishing Group
- Year
- 2014
- Tongue
- English
- Weight
- 759 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1471-0056
- DOI
- 10.1038/nrg3679
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A quadrivariate quantitative genetic analysis detected significant heritabilities for four simulated quantitative traits (Q1 -Q4) with additive genetic pleiotropy between traits Q1, 42, and 43. Using univariate segregation analysis, we tentatively detected five major loci: one each for 42, 43, and 4
Estimation of parameters in a genetic model can be very difficult using likelihood theory when there is no concise functional form for the likelihood function. An alternative method bawd on fitting the characteristic function is suggested and this method may be used on data with consistent familial