## Abstract Investigators interested in whether a disease aggregates in families often collect caseβcontrol family data, which consist of disease status and covariate information for members of families selected via case or control probands. Here, we focus on the use of caseβcontrol family data to
Estimation Problems in Fitting Genetic Models to Familial Data
β Scribed by Dr. C. A. McGilchrist
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 252 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0323-3847
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β¦ Synopsis
Estimation of parameters in a genetic model can be very difficult using likelihood theory when there is no concise functional form for the likelihood function. An alternative method bawd on fitting the characteristic function is suggested and this method may be used on data with consistent familial composition.
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