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Discovery of the ubiquitin proteasome system and its involvement in apoptosis

✍ Scribed by Melino, G


Book ID
110017044
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
73 KB
Volume
12
Category
Article
ISSN
1350-9047

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## Abstract The lysosomal apoptosis pathway is a potentially interesting therapeutic target. Since apoptosis involving the lysosomal pathway has been described to involve cathepsins, we screened a drug library for agents that induce cathepsin‐dependent apoptosis. Using pharmacological inhibitors an