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State of the Art: Targeting the Ubiquitin-Proteasome System for Drug Discovery

✍ Scribed by Sachiko Tsukamoto; Hideyoshi Yokosawa


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Most therapeutic drugs distribute to the whole body, which results in general toxicity and poor acceptance of the treatments by patients. The targeted delivery of chemotherapeutics to defined cells, either stromal or cancer cells in cancer lesions, or defined inflammatory cells in immun