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Discovery of ( R )-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5- a ]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

✍ Scribed by Li, Hui; Tatlock, John; Linton, Angelica; Gonzalez, Javier; Jewell, Tanya; Patel, Leena; Ludlum, Sarah; Drowns, Matthew; Rahavendran, Sadayappan V.; Skor, Heather; Hunter, Robert; Shi, Stephanie T.; Herlihy, Koleen J.; Parge, Hans; Hickey, Michael; Yu, Xiu; Chau, Fannie; Nonomiya, Jim; Lewis, Cristina

Book ID: 118249255
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 277 KB
Volume: 52
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm8014537

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