✦ LIBER ✦

Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach

✍ Scribed by Peng Zhan; Wenmin Chen; Zhenyu Li; Xiao Li; Xuwang Chen; Ye Tian; Christophe Pannecouque; Erik De Clercq; Xinyong Liu

Book ID: 117999837
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 491 KB
Volume: 20
Category: Article
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2012.09.058

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of novel pyridazinylthioacetam

Discovery of novel pyridazinylthioacetamides as potent HIV-1 NNRTIs using a structure-based bioisosterism approach

✍ Song, Yu’ning; Zhan, Peng; Kang, Dongwei; Li, Xiao; Tian, Ye; Li, Zhenyu; Chen, 📂 Article 📅 2013 🏛 The Royal Society of Chemistry 🌐 English ⚖ 741 KB

Arylazolylthioacetanilide. Part 8☆: Desi

Arylazolylthioacetanilide. Part 8☆: Design, synthesis and biological evaluation of Novel 2-(2-(2,4-Dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides As Potent HIV-1 inhibitors

✍ Peng Zhan; Xuwang Chen; Xiao Li; Dongyue Li; Ye Tian; Wenwen Chen; Christophe Pa 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 298 KB

Structure-Based Design of Novel HIV Prot

Structure-Based Design of Novel HIV Protease Inhibitors: Sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors

✍ Thaisrivongs, Suvit; Janakiraman, Musiri N.; Chong, Kong-Teck; Tomich, Paul K.; 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 468 KB

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide- Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors.

✍ S. THAISRIVONGS; K. D. WATENPAUGH; W. J. HOWE; P. K. TOMICH; L. A. DOLAK; K.-T. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design of Novel HIV Protease Inhibitors: Sulfonamide- Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non- Peptidic Inhibitors.

✍ S. THAISRIVONGS; M. N. JANAKIRAMAN; K.-T. CHONG; P. K. TOMICH; L. A. DOLAK; S. R 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

2-Aminothiazole as a Novel Kinase Inhibi

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase Inhibitor

✍ Das, Jagabandhu; Chen, Ping; Norris, Derek; Padmanabha, Ramesh; Lin, James; Moqu 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 396 KB