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Discovery of N -[2-[2-[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]- N -methyl-4-morpholineacetamide as a Novel and Potent Inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH) with Excellent in Vivo Activity.

✍ Scribed by Murali Dhar, T. G.; Shen, Zhongqi; Guo, Junqing; Liu, Chunjian; Watterson, Scott H.; Gu, Henry H.; Pitts, William J.; Fleener, Catherine A.; Rouleau, Katherine A.; Sherbina, N. Z.; McIntyre, Kim W.; Shuster, David J.; Witmer, Mark R.; Tredup, Jeffrey A.; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Cheney, Daniel L.; MacMaster, John F.; Miller, Laura M.; Berry, Karen K.; Harper, Timothy W.; Barrish, Joel C.; Hollenbaugh, Diane L.; Iwanowicz, Edwin J.

Book ID: 126305173
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 19 KB
Volume: 45
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm020366h

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