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Discovery of N -[(1 S ,2 S )-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity

✍ Scribed by Lin, Linus S.; Lanza,, Thomas J.; Jewell, James P.; Liu, Ping; Shah, Shrenik K.; Qi, Hongbo; Tong, Xinchun; Wang, Junying; Xu, Suoyu S.; Fong, Tung M.; Shen, Chun-Pyn; Lao, Julie; Xiao, Jing Chen; Shearman, Lauren P.; Stribling, D. Sloan; Rosko, Kimberly; Strack, Alison; Marsh, Donald J.; Feng, Yue; Kumar, Sanjeev; Samuel, Koppara; Yin, Wenji; Van der Ploeg, Lex H. T.; Goulet, Mark T.; Hagmann, William K.

Book ID: 125888148
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 85 KB
Volume: 49
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm060996+

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