✦ LIBER ✦

Discovery of Imidazo[1,5- c ]imidazol-3-ones: Weakly Basic, Orally Active Factor Xa Inhibitors

✍ Scribed by Imaeda, Yasuhiro; Kuroita, Takanobu; Sakamoto, Hiroki; Kawamoto, Tetsuji; Tobisu, Mamoru; Konishi, Noriko; Hiroe, Katsuhiko; Kawamura, Masaki; Tanaka, Toshimasa; Kubo, Keiji

Book ID: 121710909
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 993 KB
Volume: 51
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm701548u

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of 1-(3‘-Aminobenzisoxazol-5‘-

Discovery of 1-(3‘-Aminobenzisoxazol-5‘-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2‘-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride (Razaxaban), a Highly Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor

✍ Quan, Mimi L.; Lam, Patrick Y. S.; Han, Qi; Pinto, Donald J. P.; He, Ming Y.; Li 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 319 KB

Discovery of N-[2-[5-[Amino(imino)methyl

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa1

✍ Phillips, Gary B.; Buckman, Brad O.; Davey, David D.; Eagen, Keith A.; Guilford, 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 178 KB

ChemInform Abstract: Discovery of N-[2-[

ChemInform Abstract: Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro-6- [3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl] -N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa.

✍ M. M. MORRISSEY; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Discovery of 1-(2-Aminomethylphenyl)-3-t

Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl- N - [3-fluoro-2‘-(aminosulfonyl)[1,1‘-biphenyl)]-4-yl]-1 H -pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor 1

✍ Pruitt, James R.; Pinto, Donald J. P.; Galemmo,, Robert A.; Alexander, Richard S 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 555 KB

Discovery of 1-[3-(Aminomethyl)phenyl]-N

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa1

✍ Pinto, Donald J. P.; Orwat, Michael J.; Wang, Shuaige; Fevig, John M.; Quan, Mim 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 320 KB

Discovery of the Novel Antithrombotic Ag

Discovery of the Novel Antithrombotic Agent 5-Chloro- N -({(5 S )-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): An Oral, Direct Factor Xa Inhibitor

✍ Roehrig, Susanne; Straub, Alexander; Pohlmann, Jens; Lampe, Thomas; Pernerstorfe 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 349 KB