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Discovery of Dipeptide-Derived Catalysts for the Enantioselective Addition of Dimethylzinc to Aldehydes

โœ Scribed by Seock Yong Kang; Yong Sun Park


Book ID
112082773
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
309 KB
Volume
2012
Category
Article
ISSN
1434-193X

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A mechanistic model for the enantioselective addition of diethylzinc to benzaldehyde with chiral tridentate lithium complexes as catalysts correctly predicts the observed direction of enantioselectivity which occurs at levels of 8595% ee. A recent paper from these laboratories described two rationa