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Discoordinate gene expression of aggrecan and type ii collagen in experimental osteoarthritis

✍ Scribed by John R. Matyas; Mark E. Adams; Dingqiu Huang; Linda J. Sandell


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
555 KB
Volume
38
Category
Article
ISSN
0004-3591

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## Abstract The goal of this study was to examine the simultaneous effects of mechanical compression of chondrocytes on mRNA expression and macromolecular synthesis of aggrrecan and type‐II collagen. Bovine cartilage explants were exposed to different magnitudes and durations of applied mechanical