Postnatal Development of Type II Collagen and Aggrecan mRNA Expression in a Rabbit Craniomandibular Joint

Compressive compared with tensile loadin

Compressive compared with tensile loading of medial collateral ligament scar in vitro uniquely influences mRNA levels for aggrecan, collagen type II, and collagenase

✍ Tokifumi Majima; Linda L. Marchuk; Paul Sciore; Nigel G. Shrive; Cyril B. Frank; 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 843 KB

## Abstract To test the hypothesis that loading conditions can be used to engineer early ligament scar behaviors, we used an __in vitro__ system to examine the effect that cyclic hydrostatic compression and cyclic tension applied to 6‐week rabbit medial collateral ligament scars had on mRNA levels