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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery

✍ Scribed by Bartel, M A; Weinstein, J R; Schaffer, D V

Book ID: 111872745
Publisher: Nature Publishing Group
Year: 2012
Tongue: English
Weight: 451 KB
Volume: 19
Category: Article
ISSN: 0969-7128
DOI: 10.1038/gt.2012.20

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## Abstract ## Background Viruses are being exploited as vectors to deliver therapeutic genetic information into target cells. The success of this approach will depend on the ability to overcome current limitations, especially in terms of safety and efficiency, through molecular engineering of the