## Background: Gene therapy is an attractive new approach for the treatment of cancer. therefore, the development of efficient vector systems is of crucial importance in this field. different adeno-associated virus (aav) serotypes have been characterized so far, which show considerable differences
Directed evolution of adeno-associated virus for glioma cell transduction
β Scribed by Casey A. Maguire; Davide Gianni; Dimphna H. Meijer; Lev A. Shaket; Hiroaki Wakimoto; Samuel D. Rabkin; Guangping Gao; Miguel Sena-Esteves
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 363 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0167-594X
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## Abstract ## Background Adenoβassociated viral (AAV) vectors are potent delivery vehicles for gene transfer strategies directed at the central nervous system (CNS), muscle and liver. However, comparatively few studies have described AAVβmediated gene transfer to tumor tissues. We have previously