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Utility of PEGylated recombinant adeno-associated viruses for gene transfer

✍ Scribed by Hong T. Le; Qian-Chun Yu; James M. Wilson; Maria A. Croyle

Book ID
113691015
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
431 KB
Volume
108
Category
Article
ISSN
0168-3659

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## Abstract ## Background Photoreceptor (PR) and retinal pigment epithelium (RPE) are the principal cell targets in retinal gene therapy. Recombinant adeno‐associated virus (rAAV) has emerged as a very promising vector for gene therapy in hereditary retinal diseases. Gene transfer at different sta