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Directed evolution of microbial oxidative enzymes

✍ Scribed by Joel R Cherry

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
95 KB
Volume
11
Category
Article
ISSN
0958-1669

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✦ Synopsis

In the past year, a number of oxidative enzymes have been the target of directed evolution. Catalase reaction specificity has been shifted to peroxidase, the high pH, thermal and oxidative stability of a fungal peroxidase has been dramatically improved, and the substrate specificity of cytochrome P450 has been altered to include substrates that the wild-type enzymes are incapable of oxidizing.

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