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Directed evolution and the creation of enantioselective biocatalysts

โœ Scribed by K.-E. Jaeger; T. Eggert; A. Eipper; M. T. Reetz

Publisher
Springer
Year
2001
Tongue
English
Weight
203 KB
Volume
55
Category
Article
ISSN
1432-0614

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In the preceding communication in this issue we reported that the methods of directed evolution can be used to evolve enantioselective mutants of the cyclohexanone monooxygenase (CHMO) from Acinetobacter sp. NCIMB 9871 (EC 1.14.13.22) [1] as catalysts in the Baeyer-Villiger (BV) reaction of 4-hydrox