Improved biocatalysts by directed evolution and rational protein design
β Scribed by Uwe T Bornscheuer; Martina Pohl
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 134 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1367-5931
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## Abstract Provided that the industrial constraints have been properly defined, the directed evolution technologies available today enable one to design tailorβmade enzymes and biocatalytic routes for chemical processes. Family shuffling has proved to be a successful strategy using traditional rec
With the advent of directed evolution techniques, protein engineering has received a fresh impetus. Engineering proteins for thermostability is a particularly exciting and challenging field, as it is crucial for broadening the industrial use of recombinant proteins. In addition to directed evolution