## Abstract A range of aryl bromides undergo Heck reaction with ethylene glycol vinyl ether, in the presence of [PdCl(C~3~H~5~)]~2~/__cis__,__cis__,__cis__β1,2,3,4βtetrakis[(diphenylphosphanyl)methyl]cyclopentane as catalyst, to give regioselectively protected arylacetaldehydes in good yields. The
β¦ LIBER β¦
Direct Synthesis of Protected Arylacetaldehydes by Tetrakis(phosphane)palladium-Catalyzed Arylation of Ethyleneglycol Vinyl Ether.
β Scribed by Isabelle Kondolff; Henri Doucet; Maurice Santelli
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Direct Synthesis of Cyclic Ketals of Acetophenones by Palladium-Catalyzed Arylation of Hydroxylalkyl Vinyl Ethers. -It is a simple direct method to prepare ketals of acetophenones. The possibility of selective ketal formation in the presence of an additional carbonyl group is noteworthy.