ChemInform Abstract: Direct Synthesis of Cyclic Ketals of Acetophenones by Palladium-Catalyzed Arylation of Hydroxylalkyl Vinyl Ethers.
β Scribed by M. LARHED; A. HALLBERG
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Direct Synthesis of Cyclic Ketals of Acetophenones by Palladium-Catalyzed Arylation of Hydroxylalkyl Vinyl Ethers. -It is a simple direct method to prepare ketals of acetophenones. The possibility of selective ketal formation in the presence of an additional carbonyl group is noteworthy.
π SIMILAR VOLUMES
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## Abstract A range of aryl bromides undergo Heck reaction with ethylene glycol vinyl ether, in the presence of [PdCl(C~3~H~5~)]~2~/__cis__,__cis__,__cis__β1,2,3,4βtetrakis[(diphenylphosphanyl)methyl]cyclopentane as catalyst, to give regioselectively protected arylacetaldehydes in good yields. The