Direct Synthesis of Cyclic Ketals of Acetophenones by Palladium-Catalyzed Arylation of Hydroxylalkyl Vinyl Ethers. -It is a simple direct method to prepare ketals of acetophenones. The possibility of selective ketal formation in the presence of an additional carbonyl group is noteworthy.
Direct Synthesis of Cyclic Ketals of Acetophenones by Palladium-Catalyzed Arylation of Hydroxyalkyl Vinyl Ethers
β Scribed by Larhed, Mats; Hallberg, Anders
- Book ID
- 120280746
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 163 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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## Abstract A range of aryl bromides undergo Heck reaction with ethylene glycol vinyl ether, in the presence of [PdCl(C~3~H~5~)]~2~/__cis__,__cis__,__cis__β1,2,3,4βtetrakis[(diphenylphosphanyl)methyl]cyclopentane as catalyst, to give regioselectively protected arylacetaldehydes in good yields. The
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.