## Liquid chromatographic direct resolution of b-amino acids on a chiral crown ether stationary phase A chiral stationary phase (CSP) prepared by bonding (+)-(18-crown-6)-2,3,11,12tetracarboxylic acid to silica gel was used for the direct resolution of b-amino acids. To determine the optimum mobil
Direct resolution of some phenylglycines by liquid chromatography on a chiral crown ether phase
β Scribed by Peter M. Udvarhelyi; J. C. Watkins
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 410 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0899-0042
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A direct, isocratic high-performance liquid chromatographic method is described for the enantiomeric resolution of a number of phenylalkylamines, namely, racemic cathinone, amphetamine, norephedrine, and norphenylephrhe, without sample derivatization. The separations were achieved on an S-18-crownd-
## Abstract Factors influencing the stereoisomeric resolution of underivatized dipeptides and a representative tripeptide on Crownpak (CR) columns have been investigated. The elution order and relative retention suggest that a combination of chiral, steric, and hydrophobic interactions effects the
A chiral liquid chromatographic method was validated to analyze the Dand L-enantiomers of five amino acids contained in a commercial solution: aspartic acid, leucine, lysine, phenylalanine, and valine. These 10 compounds were separated on a chiral crown ether column with a mobile phase composed of w