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Direct Profiling of Multiple Enzyme Activities in Human Cell Lysates by Affinity Chromatography/Electrospray Ionization Mass Spectrometry: Application to Clinical Enzymology

✍ Scribed by Gerber, Scott A.; Scott, C. Ronald; Tureček, František; Gelb, Michael H.

Book ID
126129430
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
96 KB
Volume
73
Category
Article
ISSN
0003-2700

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## Abstract A highly sensitive, rapid assay method has been developed and validated for the estimation of omeprazole (OPZ) in human plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive‐ion mode. The assay procedure involves alkalinizatio