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Direct Organocatalytic Asymmetric Aldol Reactions of α-Amino Aldehydes: Expedient Syntheses of Highly Enantiomerically Enriched a nti -β-Hydroxy-α-amino Acids

✍ Scribed by Thayumanavan, Rajeswari; Tanaka, Fujie; Barbas, Carlos F.


Book ID
121009088
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
61 KB
Volume
6
Category
Article
ISSN
1523-7060

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## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di