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ChemInform Abstract: Efficient Synthesis of β-Hydroxy-α-amino Acid Derivatives via Direct Catalytic Asymmetric Aldol Reaction of α-Isothiocyanato Imide with Aldehydes.

✍ Scribed by Xiaohong Chen; Yin Zhu; Zhen Qiao; Mingsheng Xie; Lili Lin; Xiaohua Liu; Xiaoming Feng


Publisher
John Wiley and Sons
Year
2010
Weight
46 KB
Volume
42
Category
Article
ISSN
0931-7597

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Efficient Synthesis of β-Hydroxy-α-Amino
✍ Xiaohong Chen; Yin Zhu; Zhen Qiao; Mingsheng Xie; Lili Lin; Xiaohua Liu; Xiaomin 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 1 views

## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di