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Direct observation of simple tetrahedral intermediates

✍ Scribed by Capon, Brian; Ghosh, Ashim K.; Grieve, Duncan McL. A.


Book ID
126988014
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
877 KB
Volume
14
Category
Article
ISSN
0001-4842

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πŸ“œ SIMILAR VOLUMES


Direct observation of a tetrahedral inte
✍ Dwight R. Robinson πŸ“‚ Article πŸ“… 1968 πŸ› Elsevier Science 🌐 French βš– 204 KB

Recent experiments have led to the conclusion that the hydrolysis of the formamidinium compound, diphenylimidazolinium chloride (I, R = C6H5) proceeds through the rate determining decomposition of a tetrahedral intermediate (III) according to the mechanism of eq.1 (2).

Direct observation by X-ray analysis of
✍ B. Veerapandian; Jon B. Cooper; Andrej Ε ali; Tom L. Blundell; Robert L. Rosati; πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 652 KB

## Abstract We report the X‐ray analysis at 2.0 Γ… resolution for crystals of the aspartic proteinase endothiapepsin (EC 3.4.23.6) complexed with a potent difluorostatone‐containing tripeptide renin inhibitor (CP‐81,282). The scissile bond surrogate, an electrophilic ketone, is hydrated in the compl

Reactivity of tetrahedral intermediates
✍ McClelland, Robert A.; Santry, Linda J. πŸ“‚ Article πŸ“… 1983 πŸ› American Chemical Society 🌐 English βš– 783 KB